منابع مشابه
Bubble dynamics in DNA
The formation of local denaturation zones (bubbles) in double-stranded DNA is an important example for conformational changes of biological macromolecules. We study the dynamics of bubble formation in terms of a Fokker-Planck equation for the probability density to find a bubble of size n base pairs at time t, on the basis of the free energy in the Poland-Scheraga model. Characteristic bubble c...
متن کاملBubble dynamics in double-stranded DNA.
We report the first measurement of the dynamics of bubble formation in double-stranded DNA. Fluctuations of fluorescence of a synthetic DNA construct, internally tagged with a fluorophore and a quencher, are monitored by fluorescence correlation spectroscopy. The relaxation dynamics follow a multistate relaxation kinetics, with a characteristic time scale of 50 microseconds. A simple model of b...
متن کاملDynamics of DNA Bubble in Viscous Medium
Theoretical High Energy Physics and Instrumentation (THEPI), Department of Physics, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung 40132, Indonesia. Badan Pengkajian dan Penerapan Teknologi (BPPT) ,Jl. MH. Tahmrin 8 Jakarta , Indonesia Theoretical Physics Division, Department of Physics, Bogor Agricultural University , Kampus Darmaga, Bogor, Indonesia Indonesia Center for Theoretical and M...
متن کاملBubble relaxation dynamics in double-stranded DNA.
This paper deals with the two-state (opening-closing of base pairs) model used to describe the fluctuation dynamics of a single bubble formation. We present an exact solution for the discrete and finite size version of the model that includes end effects and derive analytic expressions of the correlation function, survival probability, and lifetimes for the bubble relaxation dynamics. It is sho...
متن کاملDNA Dynamics: Bubble ‘n’ Flip for DNA Cyclisation?
A recent demonstration of the facile in vitro formation of DNA microcircles of fewer than 100 base pairs throws new light on the basis of DNA flexibility.
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ژورنال
عنوان ژورنال: Journal of Physics A: Mathematical and Theoretical
سال: 2014
ISSN: 1751-8113,1751-8121
DOI: 10.1088/1751-8113/47/31/315003